Yes, this is possible if you have a XMP player (it is not possible with a Samsung Smart Signage Display).
Below you’ll read which cards you can use per player:
XMP6200
Micro SD Sandisk 32 GB ultra SDHC, class 10.
XMP3250 and XMP3350
32GB : SanDisk Extreme UDMA, Transcend 400x UDMA7, Afaya industrial grade CF card
16GB : SanDisk Extreme CompactFlash Card 60MB/s, Transcend 400X, Afaya industrial grade CF card
8GB : SanDisk Extreme CompactFlash Card 60MB/s, Transcend 400X, Afaya industrial grade CF card
4GB : Transcend 300X
Additional requirements for CF Card:
1. Must supports UDMA
2. Must supports > 20Mbps Read/Write